The Brotherhood was formed when a race, called the "Prophets" or "Holy Ones", united the Tugian, Kag'tar, Cogneili and Terniam and some Mizoue under their faith. They met, and allied with UNS and clashed with the Grox followers and the Cult of Attzerry. Later on, they allied the Waptoria Alliance of Species, and most recently, the Waptoria's allies the NOVA Alliance and the UFG.
The members of the Brotherhood are diffrent Races brought together by their worship of Spode. Each one is diffrent, and commit to their faith in diffrent ways. They are notably friendly towards others, and are willing to accept other religions, such as worship of the God that Will Come, as they believe all gods of good are in fact Spode.
The Brotherhood is a mildly advanced empire with a mixture of diffrent weapons, mostly Laser and Plasma weaponry, and various types of space craft. The Cogneilli and Kag'tar donate their fleets, while Terniam and Mizoue donate their weapons for the Nations. Tugian donate both.