Board Thread:Questions and Answers/@comment-108.173.247.116-20170520035702/@comment-47205-20170520081645

As explained on the other thread about this subject, the Spore disc version is often incompatible with Windows 10 because of the DRM it uses. If this is the problem in your case, using the de-authorization tool should work (it did for me).

This has the cost of preventing the game from connecting to the Spore servers, but the disc version of the game hasn't been able to do that for a few months because of a recent Spore update.

The alternative method would be to follow the method described on that Sporum post about the update - get Origin, contact EA to ask them to add Spore to your games library, providing proof of purchase in the process - but if you have limited computer time then this might not be a realistic option.