Board Thread:Questions and Answers/@comment-26288110-20151023120339/@comment-47205-20151023161906

I don't know how to solve your problem (the standard yet unreliable glitch-fixing method of un- then reinstalling after backing up your creations is the only thing I could suggest), but I know that Spore can and often does work on Windows 10. It's not supposed to work if it's the disc version unless you get rid of the SecuROM DRM, but even then the failure tends to be Spore simply refusing to load rather than having strange minor graphical glitches.