Fiction:Sombrero Galaxy

The Sombrero Galaxy (also known as Messier Object 104, M104 or NGC 4594) was a spiral galaxy in the First Gigaquadrant existing outside the general minutiae of Gigaquadrantic politics up to its destruction in the Annihilation.

The most significant civilisations in the Sombrero Galaxy were the local branch of the Grox Meta-Empire, and the Crogenitor Perception. The Crogenitors were the galaxy's most significant native lifeform. They were masters of genetic manipulation, holding lifeforms according to five specific disciplines. The Crogenitor Perception and the Sombreroan Grox Empire existed in a thousand year cold war with only minor border conflicts. The Crogenitors, in their experimentation of biotechnology, discovered the eDNA molecule, capable of incredible acts of genetic manipulation, but was unstable and created horrible mutations interlinked in a hive mind. These mutants were dubbed the Darkspore. One Crogenitor, Xylan, secretly continued eDNA experimentation and was infected himself. With secret backing from the Grox, the Darkspore were armed for a war of annihilation with the Crogenitor Perception, launching the Sombrero Galaxy into the century long Mutation Wars. The war ended abruptly with the destruction of the galaxy in the Xhodocto's Annihilation of Universe 66500.

Trivia

 * The Sombrero Galaxy was created posthumously, as to not violate the galaxy limit in the modern fiction universe
 * The galaxy serves as the canonisation and sporewikification of the events of Darkspore.